Oxygen Supplementation in COVID-19 —How Much Is Enough?

Humans are aerobic animals; we need oxygen to support metabolism and generate energy. Simply put, breathing oxygen is necessary for life. Consequently, it would make sense that diseases that inhibit the transfer of oxygen from the lung to the blood should be treated with supplementary oxygen to overcome problems associated with hypoxemia, and one should strive to achieve “normal” levels of arterial oxygen (Pao2). But is that reasoning supported by the understanding of physiology and the weight of clinical evidence?
Source: JAMA - Journal of the American Medical Association - Category: General Medicine Source Type: research