Dupilumab therapy improves gut microbiome dysbiosis and tryptophan metabolism in Chinese patients with atopic dermatitis

CONCLUSION: Dupilumab treatment tends to help shift the gut microbial dysbiosis in AD patients to a healthier state, along with improved intestinal tryptophan metabolism, suggesting the gut flora and its metabolites may mediate part of the synergistic therapeutic effects on the host.PMID:38493690 | DOI:10.1016/j.intimp.2024.111867

https://pubmed.ncbi.nlm.nih.gov/38493690/?utm_source=no_user_agent&utm_medium=rs...

Source: International Immunopharmacology - March 17, 2024 Category: Allergy & Immunology Authors: Liu Yang Danqi Li Shuomin Sun Danping Liu Yi Wang Xiaohuan Liu Bin Zhou Wenjia Nie Lu Li Yifei Wang Shanshan Sha Yan Li Chen Shen Juan Tao Source Type: research