Viability and Proliferation Assessment of Gingival Fibroblasts Cultured on Silver Nanoparticle-doped Ti-6Al-4V Surfaces

CONCLUSIONS: The findings of the present study indicate that Ti6Al4V surfaces modified with 8 nm and 30 nm AgNPs at concentrations of 100 ppm, 200 ppm, and 300 ppm do not produce any serious cytotoxicity to HGFs. The initial arrest of HGFs proliferation rate was recovered at 72 h. These results, in combination with those of the same research group, on the antibacterial activity against common periodontal pathogens, suggest that AgNP-doped Ti6Al4V surfaces are potential candidates for use in implant abutments for preventing peri-implant diseases.PMID:38457263 | DOI:10.11607/jomi.10496

Source: International Journal of Oral and Maxillofacial Implants - March 8, 2024 Category: ENT & OMF Authors: Dimitra Vasilaki Athina Bakopoulou Lambrini Papadopoulou Eleni Papachristou Nikolaos Michailidis Alexandros Tsouknidas Stergios Dratsios Thomas Taylor Konstantinos Michalakis Source Type: research