Graded and sharp transitions in semantic function in left temporal lobe

We examined two such 'connectivity gradients' reflecting the separation of (i) unimodal versus heteromodal and (ii) visual versus auditory-motor cortex, examining visually presented verbal associative and feature judgments, plus picture-based context and emotion generation. Functional responses along the first dimension sometimes showed graded change between modality-tuned and heteromodal cortex (in the verbal matching task), and other times showed sharp functional transitions, with deactivation at the extremes and activation in the middle of this gradient (internal generation). The second gradient revealed more visual than auditory-motor activation, regardless of content (associative, feature, context, emotion) or task process (matching/generation). We also uncovered subtle differences across each gradient for content type, which predominantly manifested as differences in relative magnitude of activation or deactivation.PMID:38484446 | DOI:10.1016/j.bandl.2024.105402

Source: Brain and Language - March 14, 2024 Category: Neurology Authors: Katya Krieger-Redwood Xiuyi Wang Nicholas Souter Tirso Rene Del Jesus Gonzalez Alam Jonathan Smallwood Rebecca L Jackson Elizabeth Jefferies Source Type: research