Development of porous structure for broadening Bragg-peak in scanning carbon-ion radiotherapy: Monte Carlo simulation and experimental validation

Particle radiotherapy was initially proposed by Robert Wilson in the 1940  s owing to its prominent therapeutic effects [1]. As one of the particle beams, the carbon-ion beam exhibits a relatively high linear energy transfer, which leads to a superior relative biological effectiveness (RBE) compared to proton beams [2]. The Bragg peak (BP) of a pristine carbon-ion beam i s extremely sharp, especially at low penetration depths [3]. Homogeneous coverage of the target volume could be obtained by irradiating more energy layers, which increases beam delivery time [4].
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Technical Note Source Type: research