Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood –brain barrier

A principal protective component of the mammalian blood –brain barrier (BBB) is the high expression of the multidrug efflux transporters P-glycoprotein (P-gp, encoded by ABCB1) and ABCG2 (encoded by ABCG2) on the ...

Source: Cerebrospinal Fluid Research - March 15, 2024 Category: Neurology Authors: Joanna R. Thomas, William J. E. Frye, Robert W. Robey, Andrew C. Warner, Donna Butcher, Jennifer L. Matta, Tamara C. Morgan, Elijah F. Edmondson, Paula B. Salazar, Suresh V. Ambudkar and Michael M. Gottesman Tags: Research Source Type: research