HBV DNA polymerase upregulates the transcription of PD-L1 and suppresses T cell activity in hepatocellular carcinoma

In HBV-associated HCC, T cells often exhibit a state of functional exhaustion, which prevents the immune response from rejecting the tumor and allows HCC to progress. Moreover, polymerase-specific T cells exhi...

Source: Journal of Translational Medicine - March 12, 2024 Category: Research Authors: Yan Jia, Jianing Zhao, Chunqing Wang, Jing Meng, Liqing Zhao, Hongwei Yang and Xiaoqing Zhao Tags: Research Source Type: research