Mogroside Ⅴ Inhibits M1 Polarization and Inflammation of Diabetic Mouse Macrophages via p38 MAPK/NF-Κb Signaling Pathway

CONCLUSIONS: MV suppressed M1 macrophage polarization and inflammatory response, which was partially through NF-κB and p38 MAPK in LPS+IFN-γ induced BMDMs under high glucose condition, implying the potential of MV in treatment for inflammatory complications of diabetes.PMID:38415803 | DOI:10.1080/08820139.2024.2321353

Source: Immunological Investigations - February 28, 2024 Category: Allergy & Immunology Authors: Xiaoyi Dong Zhimao Ye Cuiping Li Kongmei Li Xiaoxia Zhong Hao Li Source Type: research