Combinatorial Immunotherapy and Associated Tumor Metabolic Stress in Pre-clinical HNSCC Mmodels

The combination of conventionally fractionated radiation (conRT) and anti-PD1/PD-L1 has underperformed, speaking to a lack of understanding in the interaction between conRT and the immune response. To begin to address this issue, we have undertaken a comprehensive evaluation of conRT and PD-1/PD-L1 in pre-clinical models.

Source: International Journal of Radiation Oncology * Biology * Physics - March 14, 2024 Category: Radiology Authors: A. Gopalkrishnan, L. Yang, B. Leibowitz, A. Hefner, M. Elfayoumi, S. Basu, J. Wang, C. Pickering, H.D. Skinner Tags: 119 Source Type: research