Repurposing of Angiotensin-converting-enzyme Inhibitor on Prevention of Post-surgical Tendon Adhesion

CONCLUSION: Our results showed that ACEI is a safe and effective therapeutic candidate with potent immunomodulatory and anti-fibrotic features to alleviate surgery-induced development of fibrotic adhesive tissue. However, its efficacy needs to be further validated in clinical studies.PMID:38468533 | DOI:10.2174/0113816128284671240214080516

Source: Current Pharmaceutical Design - March 12, 2024 Category: Drugs & Pharmacology Authors: Hamideh Naimi Majid Khazaei Fariba Sharifnia Sayyed-Hadi Sayyed-Hosseinian Source Type: research