High frequency transcranial magnetic stimulation increases slow-wave activity during subsequent sleep in older adults with cognitive complaints

Slow-wave activity (SWA) during non-rapid eye movement (NREM) sleep is critical for restoring neuronal homeostasis and is associated with better cognitive function among older adults [1]. SWA declines with aging, which may contribute to various forms of age-related pathology [2] and functional decline [3]. Enhancing SWA with methods that do not interfere with sleep or daytime function could potentially mitigate these age-related problems [1]. However, SWA is highly stable within an individual from night to night [4], making SWA enhancement a challenge.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - March 13, 2024 Category: Neurology Authors: Kristine A. Wilckens, Ahmad Mayeli, Michelle E. Stepan, Christine W. Peng, Rima F. Habte, Kamakashi Sharma, Sabine A. Janssen, Savannah L. Applegate, Meredith L. Wallace, Daniel J. Buysse, Fabio Ferrarelli Source Type: research