Discovery of a novel small molecule as CD47/SIRP α and PD-1/PD-L1 dual inhibitor for cancer immunotherapy

Targeting the tumor microenvironment (TME) has emerged as a promising strategy in cancer treatment, particularly through the utilization of immune checkpoint blockade (ICB) agents such as PD-1/PD-L1 inhibitors...

Source: Cell Communication and Signaling - March 11, 2024 Category: Molecular Biology Authors: Shengzhe Jin, Hongfei Wang, Yang Li, Jingwen Yang, Beibei Li, Peishang Shi, Xiangrui Zhang, Xiaowen Zhou, Xiuman Zhou, Xiaoshuang Niu, Menghan Wu, Yahong Wu, Wenjie Zhai, Yuanming Qi, Yanfeng Gao and Wenshan Zhao Tags: Research Source Type: research