Expression of SMADs in orthotopic human endometrium, ovarian endometriosis, and endometriotic lesions in a murine model

In conclusion, these results suggest that activin A activates the SMAD signaling pathway and promotes the development of endometriotic lesions, thus identifying SMAD7 as a potential therapeutic target for endometriosis.PMID:38417880 | DOI:10.1507/endocrj.EJ23-0486

Source: Endocrine Journal - February 28, 2024 Category: Endocrinology Authors: Yuri Kadota Takeshi Kato Kana Kasai Takako Kawakita Misaki Murayama Akari Shinya Hikari Sasada Sachiko Katayama Mari Nii Shota Yamamoto Hiroki Noguchi Kou Tamura Hidenori Aoki Miyu Taniguchi Tomotaka Nakagawa Takashi Kaji Masato Nishimura Riyo Kinouchi Ka Source Type: research