Redox-neutral zinc-catalyzed cascade [1,4]-H shift/annulation of diaziridines with donor-acceptor aziridines

Chem Commun (Camb). 2024 Mar 6. doi: 10.1039/d4cc00226a. Online ahead of print.ABSTRACTThe coupling of diaziridines with donor-acceptor aziridines (DAAs) has been achieved using Zn-catalysis to furnish imidazopyrazole-4,4-dicarboxylates via [1,4]-hydride shift. The use of Zn-catalysis, [1,4]-hydride shift, natural product modification and a late-stage molecular docking study are important practical features.PMID:38445334 | DOI:10.1039/d4cc00226a

Source: Chemical Communications - March 6, 2024 Category: Chemistry Authors: Swati Samantaray Prabhat Kumar Maharana Subhradeep Kar Sharajit Saha Tharmalingam Punniyamurthy Source Type: research