Optimizing platelet inhibition in peripheral artery disease: A comparison of mono-antiplatelet therapy and dual-antiplatelet therapy using thromboelastography

CONCLUSIONS: Patients on DAPT showed a significant increase in platelet inhibition when compared to initial aspirin MAPT. A significant difference in AA %platelet inhibition was shown for patients on DAPT when compared to initial clopidogrel MAPT. The results show that patients may benefit from DAPT post-revascularization. Personalizing antiplatelet therapy with objective viscoelastic testing to confirm adequate treatment may be the next step in optimizing patient outcomes to reduce thrombosis in PAD patients.PMID:38441042 | DOI:10.1177/17085381241237005

Source: Vascular - March 5, 2024 Category: Surgery Authors: Ivy Lee Sasha Suarez Ryan Hall Monica Majumdar Tiffany Bellomo Samuel Jessula Kathryn Nuzzolo Douglas M Jefferson Nikolaos Zacharias Anahita Dua Source Type: research