Baseline shift corrections towards the heart: External validation of the impact on survival in early-stage NSCLC patients

Radiation dose to the heart is associated with poorer survival in patients treated with radiotherapy for non-small cell lung cancer (NSCLC)[1]. Research has shown the negative effects of cardiac dose on overall survival (OS)[1 –4], non-cancer death[5] and cardiac events[6,7]. While current efforts are directed at reducing cardiac dose when the radiation treatment is planned[8,9], anatomical variations during treatment[10] may cause the delivered dose to deviate from the planned dose, thus posing additional risk factors [11,12].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research