European association of urology risk stratification predicts outcome in patients receiving PSMA-PET-planned salvage radiotherapy for biochemical recurrence following radical prostatectomy

In cases of localized prostate cancer, both radical prostatectomy and external beam radiotherapy provide excellent long-term results; however, approximately 30 –50 % of patients with intermediate- and high-risk prostate cancer experience biochemical recurrence (BR) within 10 years following treatment [1]. Salvage radiotherapy (SRT), with or without androgen deprivation (ADT), provides a potential cure for patients with BR after RP [2,3]. While SRT ha s a well-established effect on biochemical progression-free survival [4], its impacts on overall survival (OS) and cancer-specific survival (CSS) seem to be limited to a subgroup of high-risk patients [4,5].

Source: Radiotherapy and Oncology - March 6, 2024 Category: Radiology Authors: Sophia Scharl, Constantinos Zamboglou, Iosif Strouthos, Andrea Farolfi, Francesca Serani, Stefan A. Koerber, J ürgen Debus, Jan C. Peeken, Marco M.E. Vogel, Stephanie G.C. Kroeze, Matthias Guckenberger, Manuel Krafcsik, George Hruby, Louise Emmett, Nina- Tags: Original Article Source Type: research