Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice
CONCLUSIONS: Our results demonstrate the involvement of PKM2-mediated glycolysis in Tfh cell differentiation and SLE pathogenesis, and PKM2 could be a key therapeutic target for the treatment of SLE.PMID:38428341 | DOI:10.1016/j.jaut.2024.103198
Source: Journal of Autoimmunity - Category: Allergy & Immunology Authors: Manna Lin Liuting Huang Junxia Huang Jia Yu Xue Yang Ji Yang Source Type: research
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