Pharmacotherapy for Alcohol Use Disorder

To the Editor In a recent systematic review and meta-analysis, McPheeters and colleagues compared the efficacy and comparative efficacy of 9 therapies for alcohol use disorder from 118 clinical trials including 20  976 adults. The findings support the use of 50 mg/d of oral naltrexone and acamprosate as first-line pharmacotherapies for alcohol use disorder. However, I have several concerns about this article.
Source: JAMA - Category: General Medicine Source Type: research