Recruitment of ubiquitin E2 enzymes is determined jointly by the U ‐box domains and substrates of E3 ligases

This study reveals the influence of substrates and U-box domains on E2 recruitment, providing a novel perspective on the function of U-box domains of E3 ligases.

Source: FEBS Letters - March 5, 2024 Category: Biochemistry Authors: Bo Jin, Bei Li, Junyao Qu, Yiheng Sun, Mengran Wang, Changjiang Yang, Yuchen Fan, Yanan Wang, Peng Xu, Haiying Sun, Bo Jiang, Bo Zhao Tags: Research Letter Source Type: research