Lymphopenia is associated with broad host response aberrations in community-acquired pneumonia

Lymphopenia at hospital admission occurs in over one-third of patients with community-acquired pneumonia (CAP), yet its clinical relevance and pathophysiological implications remain underexplored. We evaluated outcomes and immune features of patients with lymphopenic CAP (L-CAP), a previously described immunophenotype characterized by admission lymphocyte count

Source: Journal of Infection - February 29, 2024 Category: Infectious Diseases Authors: Susanne E. Doeleman, Tom D.Y. Reijnders, Sebastiaan C.M. Joosten, Alex R. Schuurman, Tjitske S.R. van Engelen, Jan Verhoeff, Valentine L éopold, Xanthe Brands, Bastiaan W. Haak, Jan M. Prins, Maadrika M.N.P. Kanglie, Inge A.H. van den Berk, Daniël R. Fa Source Type: research