Enhanced selective discrimination of point-mutated viral RNA through false amplification regulatory direct insertion in rolling circle amplification

In this study, the limit of detection was 400 aM for viral RNA, and we successfully identified a dominant SNP variant selectively. Clinical tests were also conducted.PMID:38412685 | DOI:10.1016/j.bios.2024.116145

Source: Biosensors and Bioelectronics - February 27, 2024 Category: Biotechnology Authors: Hakbeom Lee Juneseok You Hansol Lee Woojoo Kim Kuewhan Jang Jinsung Park Sungsoo Na Source Type: research