Severe Left Main Coronary Artery Stenosis and Aortic Regurgitation in a Patient Presenting with Takayasu Arteritis

Intern Med. 2024 Feb 26. doi: 10.2169/internalmedicine.3032-23. Online ahead of print.ABSTRACTWe herein report the case of a 46-year-old woman with Takayasu arteritis (TA), severe stenosis in the left main coronary artery (LMCA), and severe aortic regurgitation. Prednisolone and tacrolimus were initiated as TA treatments. Two months after initiating medical therapy, the aortic regurgitation severity improved to a moderate grade, although there was no obvious improvement in LMCA stenosis. Thus, after confirming the resolution of inflammation, we performed coronary artery bypass grafting alone without any aortic valve intervention. In TA patients with severe LMCA stenosis, surgical management of the coronary artery should therefore be considered only after successfully administering anti-inflammatory therapy.PMID:38403770 | DOI:10.2169/internalmedicine.3032-23

Source: Internal Medicine - February 25, 2024 Category: Internal Medicine Authors: Akiko Tanihata Atsushi Shibata Kazutoshi Teragaki Toshitake Yoshida Ryoko Kitada Akimasa Morisaki Asahiro Ito Yasuhiro Izumiya Daiju Fukuda Source Type: research