Demotion of canonical/non-canonical inflammasome and pyroptosis alleviates ischemia/reperfusion-induced acute kidney injury: Novel role of the D2/D3 receptor agonist ropinirole

In conclusion, ropinirole has the potential to be a reno-therapeutic treatment against I/R insult by abating the inflammatory NLRP3 inflammasome signal, pyroptosis, and oxidative stress.PMID:38402931 | DOI:10.1016/j.ejphar.2024.176460

Source: European Journal of Pharmacology - February 25, 2024 Category: Drugs & Pharmacology Authors: Nada T Henedak Hanan S El-Abhar Dalaal M Abdallah Kawkab A Ahmed Ayman A Soubh Source Type: research