Evaluation of Proflo-U ® Platform: A Novel Fluorescence-Based Point of Care Device for Quantitative Estimation of Urine Albumin

This study compares Proflo-U ® a novel PoC device that estimates urine albumin, with standard immunoturbidity based assays. Proflo-U® is a novel PoC device which works with an android based mobile application by Bluetooth connectivity. This unique fluorescence-based urine albumin assay has been compared with the well-establis hed gold standard Immunoturbidity based method on Beckman Coulter AU platform and also using Biosystem kit. The Proflo-U® generated data from standard recombinant human serum albumin (rHSA) and human urine spiked with rHSA has shown high correlationR2 ~ 0.99 andp >  0.05. This novel platform has scored 115 out of 150 among 30 parameters to determine its suitability for point of care deployment. The fluorescence-based urine albumin assay of the novel Proflo-U® platform comparable with the gold standards in the field, is easy to use, and found to be deployabl e as a point of care device.
Source: Indian Journal of Clinical Biochemistry - Category: Biochemistry Source Type: research