Diminished airway host innate response in people with cystic fibrosis who experience frequent pulmonary exacerbations

Conclusions
A diminished innate host protein defence may play a role in the pathophysiological mechanisms of frequent CF pulmonary exacerbations. Frequent exacerbators may benefit from therapies targeting this dysregulated host immune response.

Source: European Respiratory Journal - February 22, 2024 Category: Respiratory Medicine Authors: Houston, C. J., Alkhatib, A., Einarsson, G. G., Tunney, M. M., Taggart, C. C., Downey, D. G. Tags: CF and non-CF bronchiectasis Original Articles: Cystic fibrosis Source Type: research