Glucose intolerance in acromegaly is driven by low insulin secretion; results from an intravenous glucose tolerance test

ConclusionWe demonstrated that low insulin secretion is the main driver behind glucose intolerance in acromegaly. Compared to NGT and IGT controls with obesity, patients with NGT or IGT acromegaly had higher Si. Together, these findings suggest that impaired insulin secretion might be a specific mechanism for glucose intolerance in acromegaly.
Source: Pituitary - Category: Endocrinology Source Type: research