Calpain inhibition protects against atrial fibrillation by mitigating diabetes-associated atrial fibrosis and calcium handling dysfunction in type 2 diabetes mice

Diabetes mellitus (DM) is a major risk factor for atrial structural remodeling and atrial fibrillation (AF). Calpain activity is hypothesized to promote atrial remodeling and AF.

Source: Heart Rhythm - February 21, 2024 Category: Cardiology Authors: Qing Wang, Jinxiang Yuan, Hua Shen, Qi Zhu, Biyi Chen, Jinxi Wang, Weizhong Zhu, Mark A. Yorek, Duane D. Hall, Zhinong Wang, Long-Sheng Song Source Type: research