Sputum Transcriptomics Reveals FCN1+ Macrophage Activation in Mild Eosinophilic Asthma Compared to Non-Asthmatic Eosinophilic Bronchitis

CONCLUSIONS: FCN1+ macrophage activation associated with airway remodeling processes was upregulated in EA compared to that in EB, which may contribute to airway hyperresponsiveness and airflow obstruction.PMID:38262391 | PMC:PMC10823142 | DOI:10.4168/aair.2024.16.1.55

Source: Allergy, Asthma and Immunology Research - January 23, 2024 Category: Allergy & Immunology Authors: Wenzhi Zhan Wei Luo Yulong Zhang Keheng Xiang Xiaomei Chen Shuirong Shen Chuqing Huang Tingting Xu Wenbin Ding Yuehan Chen Mingtong Lin Xinghua Pan Kefang Lai Source Type: research