The role of Atrioventricular Delay in Determining Right Ventricle Function with Left Bundle Pacing

We read with great interest the paper by Tian et al1 on the effects with left bundle branch pacing (LBBP) on RV function. The authors are to be congratulated on their study, which further adds to our understanding of LBBP. However, the authors did not report if the atrioventricular delay (AVD) was optimized for each patient. This is a key detail for interpreting these results. Previous experimental2 and simulation3 studies have shown that the effect of LBBP on RV activation is highly dependent on the AVD, with AVD optimization allowing fusion between intrinsic RV and LV paced activation, reducing the right bundle branch block pattern induced by LBBP alone.

Source: Heart Rhythm - February 19, 2024 Category: Cardiology Authors: Marina Strocchi, Steven A. Niederer, Christopher A. Rinaldi Source Type: research