Detection of a historic reservoir of bedaquiline/clofazimine resistance-associated variants in Mycobacterium tuberculosis

ConclusionsThe presence of a pre-existing reservoir ofMtb strains carrying bedaquiline RAVs prior to its clinical use augments the need for rapid drug susceptibility testing and individualised regimen selection to safeguard the use of bedaquiline in TB care and control.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research