Novel Adiponectin Receptor Agonist Inhibits Cholangiocarcinoma via Adenosine Monophosphate-activated Protein Kinase

CONCLUSIONS: AdipoR1 and p-AMPKα are impaired in CCA tissues, and AdipoRon effectively inhibits CCA in vitro and in vivo. Thus, AdipoRon may be considered as a potential anti-tumor therapy in CCA.PMID:38361349 | DOI:10.2174/0109298673254969231122114107

Source: Current Medicinal Chemistry - February 16, 2024 Category: Chemistry Authors: Khac Cuong Bui Mai Ly Thi Nguyen Samarpita Barat Tim Scholta Jun Xing Vikas Bhuria Bence Sipos Ludwig Wilkens Toan Nguyen Linh Song Le Huu Thirumalaisamy P Velavan Przemyslaw Bozko Ruben R Plentz Source Type: research