Dynamic cultivation of human mesenchymal stem/stromal cells for the production of extracellular vesicles in a 3D bioreactor system

CONCLUSION: The production of MSC-EVs in a 3D bioreactor system under hypoxic conditions resulted in increased EV concentration and purity. This system could be especially useful in screening culture conditions for the production of 3D-derived MSC-EVs.PMID:38349512 | DOI:10.1007/s10529-024-03465-4

Source: Biotechnology Letters - February 13, 2024 Category: Biotechnology Authors: Ciarra Almeria Ren é Weiss Maike Keck Viktoria Weber Cornelia Kasper Dominik Egger Source Type: research