The impact of circulating tumor cell HOXB13 RNA detection in men with metastatic castration-resistant prostate cancer treated with abiraterone or enzalutamide

CONCLUSION: Higher CTC HOXB13 expression is associated with AR-dependent biomarkers in CTCs and is adversely prognostic in the context of potent AR inhibition in men with mCRPC.PMID:38236581 | DOI:10.1158/1078-0432.CCR-23-3017

Source: Clinical Cancer Research - January 18, 2024 Category: Cancer & Oncology Authors: Susan Halabi Siyuan Guo Joseph J Park David M Nanus Daniel J George Emmanuel S Antonarakis Daniel Costin Danila Russell Zelig Szmulewitz Donald P McDonnell John D Norris Changxue Lu Jun Luo Andrew J Armstrong Source Type: research