Clinical and genomic predictors of adverse events in newly diagnosed glioblastoma

CONCLUSION: Genomic biomarkers based on functional variant analysis of a routine clinical panel may help identify adverse events in GBM, particularly seizures. Identifying these risk factors could improve the management of patients through better supportive care and consideration of prophylactic therapies.PMID:38252427 | DOI:10.1158/1078-0432.CCR-23-3018

Source: Clinical Cancer Research - January 22, 2024 Category: Cancer & Oncology Authors: Mary Jane Lim-Fat J Bryan Iorgulescu Rifaquat Rahman Varun Bhave Alona Muzikansky Eleanor Woodward Sydney Whorral Marie Allen Mehdi Touat Xiaomei Li Gongwen Xu Jay Patel Elizabeth R Gerstner Jayashree Kalpathy-Cramer Gilbert Youssef Ugonma Chukwueke J Ric Source Type: research