A new subset of common variable immune deficiency characterized by reduced C1 esterase inhibitor levels

Common variable immune deficiency (CVID) is a common form of severe antibody deficiency. CVID is characterized by infections, gastrointestinal disorders, autoimmune diseases, and increased susceptibility to malignant neoplasms.1 Patients with CVID lack the ability to make a sufficient amount of antibodies to protect them from infections. Intravenous immunoglobulin (IVIG) is used for replacement therapy at 400 to 800 mg/kg and has been found to reduce infection rates for all forms of primary immunodeficiency.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letter Source Type: research