Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia

CONCLUSIONS: The PCD airway epithelium does not optimally clear antigens and is subject to oxidative and nitrosative stress. Oxidation associated with antigen stasis could represent a therapeutic target in PCD, one with convenient monitoring biomarkers.PMID:38318660 | DOI:10.1152/ajplung.00208.2022

Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - February 6, 2024 Category: Cytology Authors: Benjamin Gaston Laura Smith Michael D Davis Jessica Saunders Ivana Daniels Amjad Horani Steven L Brody Olivia Giddings Yi Zhao Nadzeya Marozkina Source Type: research