METTL3 modification of circStk4 affects mouse glomerular messangial cell autophagy, proliferation and apotosis by regulating miR-133a-3p/C1 axis

CONCLUSION: m6A modification of circStk4 mediated by METTL3 influenced circStk4 expression and impacted autophagy, proliferation and apoptosis in GMCs via the miR-133a-3p/C1 axis. This discovery introduces a novel therapeutic approach for CGN treatment.PMID:38331014 | DOI:10.1016/j.cellsig.2024.111091

Source: Cellular Signalling - February 8, 2024 Category: Cytology Authors: Xiujuan Qin Huiyu Chen Wenjia Zheng Xiaoli Zhu Jiarong Gao Source Type: research