IL1RAP Exacerbates Sepsis-Induced Pulmonary and Spleen Injury Through Regulating CD4 < sup > + < /sup > T Lymphocyte Differentiation

CONCLUSIONS: We defined IL1RAP as a new target gene through NF-κB/MAPK pathways regulating CD4+ T lymphocyte differentiation mediated the progression of sepsis, which is potentially exploitable for immunotherapy.PMID:38329477 | DOI:10.1080/08820139.2024.2312898

Source: Immunological Investigations - February 8, 2024 Category: Allergy & Immunology Authors: Liou Huang Chunrong Wu Dan Xu Yuhui Cui Jianguo Tang Source Type: research