Aberrant Lipid Metabolism in Macrophages Is Associated with Granuloma Formation in Sarcoidosis

CONCLUSIONS: Together, our findings show that altered lipid metabolism in sarcoidosis macrophages is associated with its predisposition to granuloma formation and suggest cholesterol-reducing therapies as a treatment option in patients.PMID:38353578 | DOI:10.1164/rccm.202307-1273OC

Source: Am J Respir Crit Car... - February 14, 2024 Category: Intensive Care Authors: Clarice X Lim Anna Redl Lisa Kleissl Ram Vinay Pandey Carolina Mayerhofer Thomas El Jammal Mario Mazic Karine Gonzales Nyamdelger Sukhbaatar Thomas Krausgruber Christoph Bock Markus Hengstschl äger Alain Calender Yves Pacheco Georg Stary Thomas Weichhart Source Type: research