Limiting Overdistention or Collapse when Mechanically Ventilating Injured Lungs: A Randomized Study in a Porcine Model

CONCLUSIONS: PEEP to minimize overdistention resulted in high mortality in an animal model of ARDS. Minimizing collapse or choosing a compromise between collapse and overdistention may result in less lung injury, with potential benefits of the compromise approach.PMID:38354065 | DOI:10.1164/rccm.202310-1895OC

Source: Am J Respir Crit Car... - February 14, 2024 Category: Intensive Care Authors: Mayson L A Sousa Bhushan H Katira Sheena Bouch Vanessa Hsing Doreen Engelberts Marcelo Amato Martin Post Laurent J Brochard Source Type: research