Enhancing plant biotechnology by nanoparticle delivery of nucleic acids

Trends Genet. 2024 Feb 5:S0168-9525(24)00005-2. doi: 10.1016/j.tig.2024.01.005. Online ahead of print.ABSTRACTPlant biotechnology plays a crucial role in developing modern agriculture and plant science research. However, the delivery of exogenous genetic material into plants has been a long-standing obstacle. Nanoparticle-based delivery systems are being established to address this limitation and are proving to be a feasible, versatile, and efficient approach to facilitate the internalization of functional RNA and DNA by plants. The nanoparticle-based delivery systems can also be designed for subcellular delivery and controlled release of the biomolecular cargo. In this review, we provide a concise overview of the recent advances in nanocarriers for the delivery of biomolecules into plants, with a specific focus on applications to enhance RNA interference, foreign gene transfer, and genome editing in plants.PMID:38320883 | DOI:10.1016/j.tig.2024.01.005
Source: Trends in Genetics : TIG - Category: Genetics & Stem Cells Authors: Source Type: research