DNA-dependent protein kinase regulates cytosolic double-stranded DNA secretion from irradiated macrophages to increase radiosensitivity of tumors

CONCLUSIONS: Irradiated macrophages can increase antitumor efficacy of radiotherapy through secretion of c-dsDNA under the regulation of DNA-PK.PMID:38286241 | DOI:10.1016/j.radonc.2024.110111

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - January 29, 2024 Category: Radiology Authors: Taerim Oh Gi-Sue Kang Hye-Ju Jo Hye-Joon Park Ye-Rim Lee G-One Ahn Source Type: research