Identification of genes and key pathways underlying the pathophysiological association between sarcopenia and chronic obstructive pulmonary disease

CONCLUSION: This study uncovers potential common mechanisms of COPD complicated by sarcopenia. The hub gene SAA1 and the NF-κB signaling pathway could be involved, and oxidative phosphorylation and ferroptosis might be important contributors to this comorbidity.PMID:38320732 | DOI:10.1016/j.exger.2024.112373
Source: Experimental Gerontology - Category: Geriatrics Authors: Source Type: research