OA susceptibility in mice is partially mediated by the gut microbiome, is transferrable via microbiome transplantation and is associated with immunophenotype changes

Conclusion
The gut microbiome is responsible in part for OA protection in MRL mice and is transferrable by microbiome transplantation. Transplantation induces resting systemic immunophenotyping changes that correlate with OA protection.

Source: Annals of the Rheumatic Diseases - February 15, 2024 Category: Rheumatology Authors: Prinz, E., Schlupp, L., Dyson, G., Barrett, M., Szymczak, A., Velasco, C., Izda, V., Dunn, C. M., Jeffries, M. A. Tags: ARD, Osteoarthritis Source Type: research