Inhaled antimicrobial prescribing for Pseudomonas aeruginosa infections in Europe

Cystic fibrosis (CF) is an autosomal recessive genetic condition resulting from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding the CFTR protein that regulates anion transport across epithelial cell membranes. Little to no functional CFTR activity in the airways can lead to reduced mucociliary clearance, thickened mucus, increased inflammation and infection with pathogens, such as Pseudomonas aeruginosa (P. aeruginosa) [1].
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research