Deep medullary vein damage correlates with small vessel disease in small vessel occlusion acute ischemic stroke

ConclusionThe DMV impairment was associated with the severity of cSVD, which suggests that DMV burden may be used for risk stratification in SVO-AIS patients.Clinical relevance statementThe DMV damage score, based on the association between small vessel disease and the deep medullary veins impairment, is a potential new imaging biomarker for the prognosis of small vessel occlusion acute ischemic stroke, with clinical management implications.Key Points• The damage to the deep medullary vein may be one mechanism of cerebral small vessel disease.• Severe burden of the basal ganglia perivascular space and cerebral microbleed is closely associated with significant impairment to the deep medullary vein.• The deep medullary vein damage score may reflect a risk of added vascular damage in small vessel occlusion acute ischemic stroke patients.

Source: European Radiology - February 10, 2024 Category: Radiology Source Type: research