Betulinic and ursolic acids from Nauclea latifolia roots mediate their antimalarial activities through docking with PfEMP-1 and PfPKG proteins

Chemotherapies target the PfEMP-1 and PfPKG proteins in Plasmodium falciparum, the parasite that causes malaria, in an effort to prevent the disease ’s high fatality rate. This work identified the phytochemical co...

Source: BMC Complementary and Alternative Medicine - February 7, 2024 Category: Complementary Medicine Authors: Edet Effiong Asanga, Ndifreke Daniel Ekpo, Affiong Asuquo Edeke, Chinedum Martins Ekeleme, Henshaw Uchechi Okoroiwu, Uwem Okon Edet, Ekementeabasi A. Umoh, Nikita Elkanah Umoaffia, Olorunfemi Abraham Eseyin, Ani Nkang, Monday Akpanabiatu, Jude Efiom Okoko Tags: Research Source Type: research