Outcomes Following Matched Sibling Donor Transplant for Severe Combined Immunodeficiency: A Report from the Pidtc

Hematopoietic cell transplant (HCT) for SCID using an HLA-matched sibling donor (MSD) is associated with excellent survival and low risk of morbidity and GVHD. In the largest cohort of MSD outcomes in SCID patients to date, we examined the impact on survival and immune recovery of 1) use of a conditioning regimen and 2) GVHD prophylaxis approach.

Source: Biology of Blood and Marrow Transplantation - February 1, 2024 Category: Hematology Authors: Ahmad Rayes, Brent Logan, Xuerong Liu, Jasmeen Dara, Rebecca H. Buckley, Joseph H. Oved, Neena Kapoor, Malika Kapadia, Sharat Chandra, Caridad Martinez, Nancy J. Bunin, Shanmuganathan Chandrakasan, Lauri M. Burroughs, Jeffrey J Bednarski, Hilary Haines, G Tags: 110 Source Type: research