Pediatric Doses Of neffy (Intranasal Nasal Spray) Demonstrate Pharmacokinetic Profiles That Are Equivalent To Epinephrine Injections Products
Epinephrine is the first-line treatment for severe allergic reactions, including anaphylaxis. Despite epinephrine ’s well documented history of safety and efficacy, patients/caregivers frequently fail to treat or delay treating severe allergic reactions, citing challenges of carrying epinephrine auto-injectors and concerns about injection. These concerns are particularly pronounced in pediatric patients, who, along with their caregivers, tend to be more anxious about injectable devices. An intranasal epinephrine spray (neffy) is being developed as a needle-free option for the treatment of severe allergic reactions.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: David Fleischer, H. Henry Li, Richard Lockey, Michael Kaliner, Wayne Shreffler, Richard Lowenthal, Sarina Tanimoto Source Type: research